Abstract
Objectives: To report the burden of chronic kidney disease (CKD) among those aged 70 and above in Iran by age, sex, and province from 1990 to 2021.
Design: Systematic analysis.
Outcome measures: Data were obtained from the Global Burden of Disease study 2021. All estimates were reported as counts and age-standardized rates per 100000 individuals, with their corresponding 95% uncertainty intervals (UIs).
Results: In 2021, CKD recorded an age-standardized prevalence of approximately 44 thousand per 100000 population among adults 70 years and older in Iran (95% UI: 39807–47784.5 per 100000). This rate meant a 5% increase compared to 1990, which was statistically significant. CKD also accounted for 8,725 deaths in the elderly population of Iran in 2021. Furthermore, disability-adjusted life years (DALY) rates were 3697.7 per 100000 population and had a 28.2% increase in the span of 1990–2021. Fars and Chahar Mahaal and Bakhtiari had the highest and lowest point prevalence per 100000 at 50357.2 and 40453.9, respectively, in the elderly population. In 2021, the prevalence, deaths, and DALYs due to CKD did not differ significantly between the two sexes, although the numbers were slightly higher in the female population. Moreover, the age-standardized prevalence, deaths, and DALYs of CKD in the elderly of Iran in 2021 started to rise in the 70–74 and increased with aging.
Conclusions: The burden of CKD in the elderly of Iran has increased over the past 30 years. This is in line with the increase in the elderly population and the rising of its related risk factors. Preemptive measures, public knowledge raising, and the implementation of risk management policies can brighten the future of Iran’s elderly population in terms of non-communicable diseases, especially CKD.